United States securities and exchange commission logo August 14, 2023 Richard Yeh Chief Financial Officer I-Mab 555 West Haiyang Road Pudong District, Shanghai, 200124 People s Republic of China Re: I-Mab Form 20-F for the Fiscal Year Ended December 31, 2022 File No. 001-39173 Dear Richard Yeh: We have completed our review of your filing. We remind you that the company and its management are responsible for the accuracy and adequacy of their disclosures, notwithstanding any review, comments, action or absence of action by the staff. Sincerely, Division of Corporation Finance Disclosure Review Program cc: Haiping Li, Esq.